Anti-FN1 Antibody Monoclonal
Catalog No : IGX-58672
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. | ||
|---|---|---|---|
| Other names | FN1, FN, Fibronectin, FN, Cold-insoluble globulin, CIG | ||
| Cellular localization | Secreted, Extracellular Matrix | ||
| Research area | Cancer, Cardiovascular, Developmental biology, Signal transduction, | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P02751 | ||
| Product name | Anti-FN1 Antibody Monoclonal | ||
|---|---|---|---|
| Catalog No | IGX-58672 | ||
| Supplier’s Catalog No | IGX-58672 | ||
| Supplier | ImuGeX | ||
| Host species | Mouse | ||
| Species reactivity | Mouse, Rat, Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:500-1:5000 | ||
| Molecular weight | |||
| Conjugate | Unconjugated | ||
| Immunogen | Synthetic Peptide | ||
| Specificity | This antibody detects total endogenous levels of FN1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Monoclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | Affinity Purified | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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