Anti-NOG Antibody Monoclonal

Catalog No : IGX-58884
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Description Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PMID:21976273, PMID:26643732).
Other names NOG, NOGG_HUMAN, Noggin, SYM 1, SYM1, Symphalangism 1 (proximal), Synostoses (multiple) syndrome 1, SYNS 1, SYNS1.
Cellular localization Secreted
Research area Developmental biology, s
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q13253
Product name Anti-NOG Antibody Monoclonal
Catalog No IGX-58884
Supplier’s Catalog No IGX-58884
Supplier ImuGeX
Host species Mouse
Species reactivity N/A
Applications ELISA, WB, ICC
Recommended dilutions WB: 1:500-1:5000, ICC: 1:50-1:200
Molecular weight
Conjugate Unconjugated
Immunogen Purified recombinant human NOG protein fragments expressed in E.coli.
Specificity This antibody detects total endogenous levels of NOG protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Monoclonal
Isotype IgG3
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Ascites
Formulation Liquid
Purification Affinity Purified
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).