Livin, Recombinant, Human (Baculoviral IAP Repeat Containing Protein 7, BIRC7, Kidney Inhibitor of Apoptosis Protein, KIAP, Livin Inhibitor of Apotosis, Melanoma Inhibitor of Apoptosis Protein, ML-IAP, RING Finger Protein 50, RNF50)

Catalog No : USB-L3180-03
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Product name Livin, Recombinant, Human (Baculoviral IAP Repeat Containing Protein 7, BIRC7, Kidney Inhibitor of Apoptosis Protein, KIAP, Livin Inhibitor of Apotosis, Melanoma Inhibitor of Apoptosis Protein, ML-IAP, RING Finger Protein 50, RNF50)
Catalog No USB-L3180-03
Supplier’s Catalog No L3180-03
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 34
Storage -20°C
Other names
Grade Highly Purified
Purity ≥ 90% by SDS-PAGE
Form Supplied as a liquid in 20mM Tris pH 8.0, 1mM DTT, 0.1M sodium chloride, 2mM EDTA, 20% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ≥ 90% by SDS-PAGE
Description Livin is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin has direct interaction with several caspases including caspase-3, -7, and –9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. Recombinant human Livin fused to His-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Source: Recombinant corresponding to aa1-298 with His-tag expressed in E. coli (NP_647478). AA Sequences: MGSSHHHHHH SSGLVPRGSH MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.