Imugex

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Categories: Peptides & Proteins / Proteins

Product name			Livin beta, Recombinant, Human, aa1-280, His-Tag (Livin inhibitor of apoptosis Isoform beta, BIRC7, KIAP, ML-IAP, MLIAP, RNF50)
Catalog No			USB-351353
Supplier’s Catalog No			351353
Supplier			US Biologicals
Source antigen			Recombinant, human from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			33.4

Storage			-20°C/-70°C
Other names
Grade			Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 2mM DTT, 300mM sodium chloride, 1mM EDTA, 40% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			Livin isoform beta is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin isoform beta has direct interaction with several caspases including caspase-3, -7, and –9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. Source: Recombinant protein corresponding to aa1-280 from human Livin beta, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~33.4kD (304aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGPKDS AKCLHRGPQP SHWAAGDGPT QERCGPRSLG SPVLGLDTCR AWDHVDGQIL GQLRPLTEEE EEEGAGATLS RGPAFPGMGS EELRLASFYD WPLTAEVPPE LLAAAGFFHT GHQDKVRCFF CYGGLQSWKR GDDPWTEHAK WFPSCQFLLR SKGRDFVHSV QETHSQLLGS WDPWEEPEDA APVAPSVPAS GYPELPTPRR EVQSESAQEP GARDVEAQLR RLQEERTCKV CLDRAVSIVF VPCGHLVCAE CAPGLQLCPI CRAPVRSRVR TFLS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.