Imugex

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Categories: Peptides & Proteins / Proteins

Product name			EIF4EBP2, Recombinant, Human, aa1-120, His-Tag (Eukaryotic translation initiation factor 4E binding protein 2)
Catalog No			USB-349886
Supplier’s Catalog No			349886
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			15.1

Storage			-20°C
Other names
Grade			Purified
Purity			~85% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.1M sodium chloride, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~85% (SDS-PAGE)
Description			EIF4EBP2 is a member of the eukaryotic translation initiation factor 4E binding protein family. This protein binds eIF4E and inhibits translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Regulation of this protein has been implicated in cell proliferation, cell differentiation and viral infection. Source: Recombinant protein corresponding to aa1-120 of human EIF4EBP2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~15.1kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MSSSAGSGHQ PSQSRAIPTR TVAISDAAQL PHDYCTTPGG TLFSTTPGGT RIIYDRKFLL DRRNSPMAQT PPCHLPNIPG VTSPGTLIED SKVEVNNLNN LNNHDRKHAV GDDAQFEMDI Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.