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Categories: Peptides & Proteins / Proteins

Product name			Thyroid Iodide Transporter, Rat (TIT) (Control Peptide)
Catalog No			USB-T5610-02
Supplier’s Catalog No			T5610-02
Supplier			US Biologicals
Source antigen			Rat synthetic peptide
Reactivity
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			Highly purified
Form			Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Reactivity life			12 months
Note			For reserch purpose only
Purity			Highly purified
Description			A 16aa peptide sequence (designated TIT11-P; control peptide), near the C-terminal, cytoplasmic domain of rat TIT. The 16-aa rat peptide sequence is unique to TIT and no significant sequence is seen with glucose transporter or other Na+-dependent transporters. Iodide (I-) is an essential constituent of thyroid hormones. Thyroid epithelial cells for the biosynthesis of thyroid hormones actively transport it. At the cellular level, Iodide transport is mediated by intrinsic membrane Na+/I+ symporter (NIS). Rat TIT (618 aa; ~66kD) is predicted to contain 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.