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Categories: Peptides & Proteins / Proteins

Product name			Vesicular Acetylcholine Transporter, Rat, Control Peptide (VAChT)
Catalog No			USB-V2121-86C
Supplier’s Catalog No			V2121-86C
Supplier			US Biologicals
Source antigen			Rat synthetic peptide
Reactivity			75% homology with the human VAT (1). No significant sequence homology is seen with other neurotransmitter transporter
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			Highly purified
Form			Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Reactivity life			12 months
Note			For reserch purpose only
Purity			Highly purified
Description			Control Peptide for V2121-86B (antiserum) and V2121-86C (affinity purified) Rat/Mouse VAChT are 530aa proteins with 12 transmembrane domains and a large intravesicular loop between TM1 and TM2. Twenty (20)aa peptide mapping within the C-terminus of rat/mouse VAT . Acetylcholine transferase synthesizes the neurotransmitter acetylcholine (ACh) from choline and acetyl CoA. ACh is packaged and stored into synaptic vesicles until its release. ACh is hydrolyzed by acetylcholine esterase (AChE) to yield choline and acetate. Choline is taken up by the high affinity VAChT/VAT located at the membrane and recycled for synthesis of ACh. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.