MUTED, Recombinant, Human, aa1-187, His-Tag (Muted homolog)

Catalog No : USB-350089
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Product name MUTED, Recombinant, Human, aa1-187, His-Tag (Muted homolog)
Catalog No USB-350089
Supplier’s Catalog No 350089
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 24
Storage -20°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 2mM DTT, 0.1mM PMSF, 1mM EDTA, 40% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description Muted homolog, also known as MuTED, is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MuTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis of lysosome related organelles complex 1 (BLOC1). Also, MuTED is ubiquitously expressed with higher levels in brain, bone marrow, kidney, and liver and lower levels in skeletal muscle. Source: Recombinant protein corresponding to aa1-187 of human MUTED, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~24kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSGGGTE TPVGCEAAPG GGSKKRDSLG TAGSAHLIIK DLGEIHSRLL DHRPVIQGET RYFVKEFEEK RGLREMRVLE NLKNMIHETN EHTLPKCRDT MRDSLSQVLQ RLQAANDSVC RLQQREQERK KIHSDHLVAS EKQHMLQWDN FMKEQPNKRA EVDEEHRKAM ERLKEQYAEM EKDLAKFSTF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.