Lcn2, Recombinant, Rat, aa21-198, His-Tag (Neutrophil gelatinase-associated lipocalin, Sip24)

Catalog No : USB-351340
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Product name Lcn2, Recombinant, Rat, aa21-198, His-Tag (Neutrophil gelatinase-associated lipocalin, Sip24)
Catalog No USB-351340
Supplier’s Catalog No 351340
Supplier US Biologicals
Source antigen Recombinant, rat from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 22.9
Storage -20°C/-70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 20% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Lcn2 also known as Neutrophil gelatinase-associated lipocalin. It belongs to the calycin superfamily and Lipocalin family. It is essential component of the antimicrobial innate immune system, is present in neutrophils and multiple other tissues. It prevents iron acquisition by microorganisms by sequestering iron-loaded bacterial siderophores. In contrast to its pro-apoptotic activity, Lcn2 has also been reported to be a survival factor. Lcn2 protected thyroid carcinoma cells from apoptosis induced by serum deprivation and silencing of Lcn2 reduced thyroid tumor growth Source: Recombinant protein corresponding to aa21-198 from rat Lcn2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~22.9kD (201aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQDSTQNL IPAPPLISVP LQPGFWTERF QGRWFVVGLA ANAVQKERQS RFTMYSTIYE LQEDNSYNVT SILVRGQGCR YWIRTFVPSS RPGQFTLGNI HSYPQIQSYD VQVADTDYDQ FAMVFFQKTS ENKQYFKVTL YGRTKGLSDE LKERFVSFAK SLGLKDNNIV FSVPTDQCID N Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.