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Categories: Peptides & Proteins / Proteins

Product name			Troponin C, 1-160aa, Recombinant, Human (fast skeletal muscle troponin C, TNNC2, sTnC)
Catalog No			USB-T8665-10A
Supplier’s Catalog No			T8665-10A
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			18.1

Storage			-70°C
Other names
Grade			Purified
Purity			≥95% (SDS-PAGE)
Form			Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, 1mM DTT, 100mM sodium chloride, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥95% (SDS-PAGE)
Description			Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Source: Recombinant human Troponin C was expressed in E.coli. Molecular Weight: 18.1kD (160aa) AA Sequence: MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.