TBCA, 1-108aa, Recombinant, Human (Tubulin folding cofactor A)

Catalog No : USB-T9157-31
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Product name TBCA, 1-108aa, Recombinant, Human (Tubulin folding cofactor A)
Catalog No USB-T9157-31
Supplier’s Catalog No T9157-31
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 12.8
Storage -70°C
Other names
Grade Purified
Purity ≥95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH7.5, 1mM DTT, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ≥95% (SDS-PAGE)
Description Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Source: Recombinant human TBCA protein was expressed in E.coli. Molecular Weight: 12.8kD (108aa) AA Sequence: MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.