Imugex

Shipping cost plus VAT not included , delivery in 7-14 business days

Categories: Peptides & Proteins / Proteins

Product name			TrkC-Fc Chimera, Human (Tropomyosin-Related Kinase Receptor, NT-3 Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 3, TrkC Tyrosine Kinase, GP145-TrkC, Trk-C, NTRK3, TRKC, TrkC-Fc Chimera)
Catalog No			USB-215492
Supplier’s Catalog No			215492
Supplier			US Biologicals
Source antigen			Human 293 cells
Reactivity
Cross reactivity
Applications
Molecular weight			8515071.9

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a lyophilized powder. Reconstitute with 500ul PBS.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			TrkC is a member of the tropomyosin-related kinase receptor family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. TrkC is a heavily glycosylated molecule with 13 potential N-linked glycosylation sites within the extracellular domain. Source: TrkC-Fc Chimera, from human DNA sequence encoding the signal peptide and extracellular domain of human TrkC aa1-428 was fused to the Fc region of human IgG1 aa93-330. The chimeric protein was expressed in modified human 293 cells. Molecular Weight: ~85kD-150kD with post-translational modification and ~71.9kD unmodified. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.