Flt3-Ligand, Recombinant, Mouse (Fms-like Tyrosine Kinase 3 Ligand, flk2 Ligand)
Catalog No : USB-219772
462.08€
0.00€
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| Product name | Flt3-Ligand, Recombinant, Mouse (Fms-like Tyrosine Kinase 3 Ligand, flk2 Ligand) | ||
|---|---|---|---|
| Catalog No | USB-219772 | ||
| Supplier’s Catalog No | 219772 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 16.4 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~98% (SDS-PAGE, HPLC) | ||
| Form | Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile dH2O to 0.1-1.0mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~98% (SDS-PAGE, HPLC) | ||
| Description | Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Source: Recombinant protein corresponding to 144aa residues from mouse Flt3-Ligand, expressed in E. coli. Molecular Weight: ~16.4kD Biological Activity: Determined by the dose-dependent proliferation of mouse AML5 cells and is typically 5-8ng/ml. Endotoxin: <0.1ng/ug (0.1EU/u) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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