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Categories: Peptides & Proteins / Proteins

Product name			Flt3 ligand, Recombinant, Human, aa27-184, His-Tag (Fms-related tyrosine Kinase 3 ligand, FLT3LG, Flt3L, FL, SL cytokine)
Catalog No			USB-351224
Supplier’s Catalog No			351224
Supplier			US Biologicals
Source antigen			Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			19

Storage			-20°C/-70°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			FLT3LG, also known as fms-related tyrosine kinase 3 ligand, is an alpha-cytokine that promotes the differentiation of multiple hematopoietic cell lineages. Also, this protein acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. FLT3LG is crucial for steady-state pDC and cDC development. It controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Source: Recombinant protein corresponding to aa27-184 from human FLT3LG, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~19kD (166aa) AA Sequence: TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAPQPLE HHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.