Imugex

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Categories: Peptides & Proteins / Proteins

Product name			ALK, Recombinant, Human, GST-Tag (Anaplastic Lymphoma Kinase, Ki-1, CD246, NBLST3, TFG/ALK)
Catalog No			USB-499771
Supplier’s Catalog No			499771
Supplier			US Biologicals
Source antigen			Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight			90

Storage			-70°C
Other names
Grade			Purified
Purity			Purified (~70-90%)
Form			Supplied as a liquid in 50mM sodium phosphate, pH 7.0, 300mM sodium chloride, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Purified (~70-90%)
Description			ALK or anaplastic lymphoma kinase is a receptor tyrosine kinase that was originally identified as a member of the insulin receptor subfamily that acquires transforming capability when truncated and fused to NPM (nucleophosmin) in the t(2;5) chromosomal rearrangement associated with ALCL Many chromosomal rearrangements leading to enhanced ALK activity have been described and are implicated in a number of cancer types. In the nervous system, ALK in the presence of ligand appears essential for axonal guidance, whereas in the absence of ligand, ALK expression can lead to developmental neuronal apoptosis. Source: Recombinant protein corresponding to human ALK, fused to GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~90kD Specific Activity: 24nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.