Imugex

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Categories: Peptides & Proteins / Proteins

Product name			PYK2, Recombinant, Human, His-Tag (Protein-tyrosine Kinase 2-beta, Calcium-dependent Tyrosine Kinase, FAK2, PTK2B, CADTK, FADK2, CAKB, PKB, PTK, RAFTK, PYK2)
Catalog No			USB-500415
Supplier’s Catalog No			500415
Supplier			US Biologicals
Source antigen			Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight			39

Storage			-70°C
Other names
Grade			Purified
Purity			Purified (~70-90%)
Form			Supplied as a liquid in 50mM NaPhosphate, pH 7.0, 300mM sodium chloride, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Purified (~70-90%)
Description			PYK2 (also known as FAK2/RAFTK) is a member of the focal adhesion PTK family. PYK2/FAK2 can be activated by a variety of extracellular signals that elevate intracellular calcium concentration, and by stress signals. Unlike FAK, which is widely expressed in various tissues and links transmembrane integrin receptors to intracellular pathways, PYK2/FAK2 is expressed mainly in the central nervous system and in cells derived from hematopoietic lineages. In osteoclasts, although FAK is expressed, PYK2/FAK2 appears to be the predominant mediator of integrin alpha(v)beta3 signaling events that influence osteoclast physiology and pathology. Source: Recombinant protein corresponding to human PYK2, fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~39kD Specific Activity: 254nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.