ROR1, Recombinant, Human, GST-Tag (Tyrosine-Protein Kinase Transmembrane Receptor ROR1, NTRKR1)

Catalog No : USB-500430
572.43€
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Product name ROR1, Recombinant, Human, GST-Tag (Tyrosine-Protein Kinase Transmembrane Receptor ROR1, NTRKR1)
Catalog No USB-500430
Supplier’s Catalog No 500430
Supplier US Biologicals
Source antigen Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight 82
Storage -70°C
Other names
Grade Purified
Purity Purified (~70-90%)
Form Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity Purified (~70-90%)
Description ROR1 is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors that play a role in the control of most basic cellular processes including cell proliferation, differentiation, migration and metabolism. Many human breast cancers express the ROR1 protein and high-level expression of ROR1 in breast adenocarcinoma is associated with aggressive disease. Silencing expression of ROR1 in human breast cancer cell lines found to express this protein impaired their growth in vitro and also in immune-deficient mice. Source: Recombinant protein corresponding to human ROR1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~82kD Specific Activity: 0.2nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.