TEC, Recombinant, Rat, GST-Tag (Tyrosine-protein Kinase, PSCTK4)

Catalog No : USB-500483
572.43€
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Product name TEC, Recombinant, Rat, GST-Tag (Tyrosine-protein Kinase, PSCTK4)
Catalog No USB-500483
Supplier’s Catalog No 500483
Supplier US Biologicals
Source antigen Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight 100
Storage -70°C
Other names
Grade Purified
Purity Purified (~70-90%)
Form Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity Purified (~70-90%)
Description TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. TEC is an integral component of T cell signaling and has a distinct role in T cell activation. Defects in TEC may be associated with myelodysplastic syndrome. TEC plays a crucial role in regulating FGF2 secretion under various physiological conditions and it inhibits CD25 expression in rat T-lymphocyte. Source: Recombinant protein corresponding to rat TEC fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~100kD Specific Activity: 2.5nmol/min/mg as per activity assay protocol. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.