Imugex

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Categories: Peptides & Proteins / Proteins

Product name			TYK2, Recombinant, Human, GST-Tag (Janus Kinases, JAKs, PSCTK4, MGC126760, MGC126762)
Catalog No			USB-500528
Supplier’s Catalog No			500528
Supplier			US Biologicals
Source antigen			Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight			110

Storage			-70°C
Other names
Grade			Purified
Purity			Purified (~70-90%)
Form			Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Purified (~70-90%)
Description			TYK2 is a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families which associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. TYK2 play a role in anti-viral immunity and TYK2 plays an indispensable role in controlling responses to multiple cytokines in humans. Tyk2 contributes selectively to signals triggered by various biologic stimuli and cytokine receptors and TYK2 is an important regulator of lymphoid tumor surveillance. Source: Recombinant protein corresponding to human TYK2 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~110kD Specific Activity: 24nmol/min/mgas per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.