Protein Gene Product 9.5, Recombinant, Human (PGP9.5, Ubiquitin CT Hydrolase L1, UCH, UCHL1, Ubiquitin thiolesterase, PARK5)
Catalog No : USB-P9102-70H
650.59€
0.00€
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| Product name | Protein Gene Product 9.5, Recombinant, Human (PGP9.5, Ubiquitin CT Hydrolase L1, UCH, UCHL1, Ubiquitin thiolesterase, PARK5) | ||
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| Catalog No | USB-P9102-70H | ||
| Supplier’s Catalog No | P9102-70H | ||
| Supplier | US Biologicals | ||
| Source antigen | Human, recombinant, E. coli | ||
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| Cross reactivity | |||
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| Molecular weight | |||
| Storage | -20°C | ||
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| Form | Supplied as a liquid in 20mM Tris-HCl pH8.0, 2mM EDTA. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | |||
| Description | PGP9.5 1-223aa PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Recombinant PGP9.5 protein was expressed in E.coli and purified by using conventional chromatography techniques. Molecular Weight: 24.8kD (223 a.a) (Real molecular weight on SDS-PAGE will be shift up) Purity: > 95% by SDS PAGE Concentration : 1 mg/ml Sequence: MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA Enzyme Activity: Specific activity is > 150 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of ubiquitin-AMC per minute at pH 7.5, at 37°C. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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