SUMO3, Recombinant, Human (Small Ubiquitin-related Modifier 3, SUMO-3, SMT3 Homolog 1, SUMO-2, Ubiquitin-like Protein SMT3A, SMT3A, SMT3H1)

Catalog No : USB-S8026-20E
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Product name SUMO3, Recombinant, Human (Small Ubiquitin-related Modifier 3, SUMO-3, SMT3 Homolog 1, SUMO-2, Ubiquitin-like Protein SMT3A, SMT3A, SMT3H1)
Catalog No USB-S8026-20E
Supplier’s Catalog No S8026-20E
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 12.6
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE).
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 20% glycerol, 0.1M sodium chloride, 1mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE).
Description SUMO3, also known as small ubiquitin-related modifier 3, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO3 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It regulates amyloid beta generation and may be critical in the onset or progression of Alzheimer’s disease. Source: Recombinant corresponding to aa1-92 of human SUMO3 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG Molecular Weight: 12.6kD (112aa) confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.