Isopeptidase T, Long Form, Recombinant, Human (ISOT, Deubiquitinating Enzyme 5, Ubiquitin Carboxyl-terminal Hydrolase 5, Ubiquitin Thioesterase 5, Ubiquitin-specific-processing Protease 5, USP5)

Catalog No : USB-I8960-01B
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Product name Isopeptidase T, Long Form, Recombinant, Human (ISOT, Deubiquitinating Enzyme 5, Ubiquitin Carboxyl-terminal Hydrolase 5, Ubiquitin Thioesterase 5, Ubiquitin-specific-processing Protease 5, USP5)
Catalog No USB-I8960-01B
Supplier’s Catalog No I8960-01B
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 97
Storage -70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 50mM tris buffered saline, 10mM b-mercaptoethanol, pH 7.5.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23aa in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active. Source: Recombinant corresponding to human Isopeptidase expressed in E. coli. Molecular Weight: ~97kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.