UBE2V1, Active, Recombinant, Human, FLAG-Tag (Ubiquitin-conjugating Enzyme E2 Variant 1, UEV-1, CROC-1, TRAF6-Regulated IKK Activator 1 Beta Uev1A, CROC1, UBE2V, UEV1, P/OKcl.19)

Catalog No : USB-137389
574.73€
0.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Product name UBE2V1, Active, Recombinant, Human, FLAG-Tag (Ubiquitin-conjugating Enzyme E2 Variant 1, UEV-1, CROC-1, TRAF6-Regulated IKK Activator 1 Beta Uev1A, CROC1, UBE2V, UEV1, P/OKcl.19)
Catalog No USB-137389
Supplier’s Catalog No 137389
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 20
Storage -70°C
Other names
Grade Purified
Purity Purified (~80%)
Form Supplied as a liquid in 45mM Tris-HCl, pH 8.0, 124mM sodium chloride, 2.4mM potassium chloride, 90ug/ml Flag peptide, 10% glycerol, 3mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity Purified (~80%)
Description Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Source: Recombinant corresponding to aa2-170 from human UEV1A, fused to FLAG-tag at N-terminal, expressed in E. coli. Molecular Weight: ~20kD Applications: Suitable for for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.