USP14, Active, Recombinant, Human, FLAG-Tag (Ubiquitin Carboxyl-terminal Hydrolase 14, Deubiquitinating Enzyme 14, Ubiquitin Thiolesterase 14, Ubiquitin-specific-processing Protease 14, TGT)
Catalog No : USB-137395
685.08€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | USP14, Active, Recombinant, Human, FLAG-Tag (Ubiquitin Carboxyl-terminal Hydrolase 14, Deubiquitinating Enzyme 14, Ubiquitin Thiolesterase 14, Ubiquitin-specific-processing Protease 14, TGT) | ||
|---|---|---|---|
| Catalog No | USB-137395 | ||
| Supplier’s Catalog No | 137395 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Sf9 cell | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 57 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | Purified (~75%) | ||
| Form | Supplied as a liquid in 45mM Tris-HCl, pH 8.0, 124mM sodium chloride, 2.4mM potassium chloride, 90ug/ml FLAG peptide, 10% glycerol, 3mM DTT. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Purified (~75%) | ||
| Description | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Source: Recombinant corresponding to aa2-494 from human USP14, fused to FLAG-tag at N-terminal, expressedin Sf9 insect cells via a baculovirus expression system. Molecular Weight: ~57kD Applications: Suitable for for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
Product Details
© 2020 Imugex All Rights Reserved