Imugex

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Categories: Peptides & Proteins / Proteins

Product name			UbcH7, Recombinant, Human (Ubiquitin Conjugating Enzyme 7)
Catalog No			USB-209290
Supplier’s Catalog No			209290
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			17.9

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95% (RP-HPLC, SDS-PAGE)
Form			Supplied as a liquid in 50mM HEPES, pH 7.5, 150mM sodium chloride, 1mM DTT, 10% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (RP-HPLC, SDS-PAGE)
Description			Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7. Source: Recombinant protein corresponding to human UbcH7, a single, non-glycosylated polypeptide chain containing 154aa, expressed in E. coli. Molecular Weight: ~17.9kD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.