SAE1, Recombinant, Human, aa1-346, His-T7 Tag (SUMO1 activating Enzyme Subunit 1, AOS1, HSPC140, SUA1, UBLE1A)
Catalog No : USB-351486
508.06€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | SAE1, Recombinant, Human, aa1-346, His-T7 Tag (SUMO1 activating Enzyme Subunit 1, AOS1, HSPC140, SUA1, UBLE1A) | ||
|---|---|---|---|
| Catalog No | USB-351486 | ||
| Supplier’s Catalog No | 351486 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, human from E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 42.2 | ||
| Storage | -20°C/-70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 10% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE) | ||
| Description | SAE1, also known as AOS1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteasome. SAE1, which is a dimeric enzyme, functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. This protein can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. Source: Recombinant protein corresponding to aa1-346 from human SAE1, fused to His-T7 tag at N-terminal expressed in E. coli. Molecular Weight: ~42.2kD (378aa) AA Sequence: MHHHHHHMAS MTGGQQMGRD LYDDDDKDRW GSMVEKEEAG GGISEEEAAQ YDRQIRLWGL EAQKRLRASR VLLVGLKGLG AEIAKNLILA GVKGLTMLDH EQVTPEDPGA QFLIRTGSVG RNRAEASLER AQNLNPMVDV KVDTEDIEKK PESFFTQFDA VCLTCCSRDV IVKVDQICHK NSIKFFTGDV FGYHGYTFAN LGEHEFVEEK TKVAKVSQGV EDGPDTKRAK LDSSETTMVK KKVVFCPVKE ALEVDWSSEK AKAALKRTTS DYFLLQVLLK FRTDKGRDPS SDTYEEDSEL LLQIRNDVLD SLGISPDLLP EDFVRYCFSE MAPVCAVVGG ILAQEIVKAL SQRDPPHNNF FFFDGMKGNG IVECLGPK Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
Product Details
© 2020 Imugex All Rights Reserved