UbcH7, Recombinant, Human (Ubiquitin-conjugating enzyme E2 L3, UBE2L3, Ubiquitin-conjugating enzyme E2-F1, L-UBC, Ubiquitin carrier protein L3, Ubiquitin protein ligase L3)
Catalog No : USB-U0880-02
459.78€
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| Product name | UbcH7, Recombinant, Human (Ubiquitin-conjugating enzyme E2 L3, UBE2L3, Ubiquitin-conjugating enzyme E2-F1, L-UBC, Ubiquitin carrier protein L3, Ubiquitin protein ligase L3) | ||
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| Catalog No | USB-U0880-02 | ||
| Supplier’s Catalog No | U0880-02 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 17.9 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS PAGE) Purified by conventional chromatography techniques. | ||
| Form | Supplied as a liquid in 50mM HEPES, pH 7.5, 150mM sodium chloride, 1mM DTT and 10% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS PAGE) Purified by conventional chromatography techniques. | ||
| Description | Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kB maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7 (NP_003338). Molecular Weight: 17.9kD (154 amino acids). Does not contain His tag. AA Sequence: MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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