CDC34, Recombinant, Human, His-Tag (Ubiquitin-conjugating Enzyme E2 R1, UBE2R1, Ubiquitin-conjugating Enzyme E2-32kD Complementing, Ubiquitin-conjugating Enzyme E2-CDC34, Ubiquitin-protein Ligase R1, UBCH3)

Catalog No : USB-C2561-01J
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Product name CDC34, Recombinant, Human, His-Tag (Ubiquitin-conjugating Enzyme E2 R1, UBE2R1, Ubiquitin-conjugating Enzyme E2-32kD Complementing, Ubiquitin-conjugating Enzyme E2-CDC34, Ubiquitin-protein Ligase R1, UBCH3)
Catalog No USB-C2561-01J
Supplier’s Catalog No C2561-01J
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 32
Storage -70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 50mM HEPES, 50mM sodium chloride, pH 8.0, 1mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description UbcH3 is a class II enzyme, homologous to Cdc34 from Saccharomyces cerevisiae, and is important in the control of cell cycle and DNA replication. UbcH3/Cdc34 in association with different E3 complexes, including SCF, has been shown to target many different substrates for ubiquitination and degradation during cell division, signal transduction, and development. UbcH3 substrates that have been characterized include IkB, Wee1, ICERIlg, p27Xic1. Source: Recombinant corresponding to human UbcH3 with His-tag, expressed in E. coli. Molecular Weight: ~32kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.