UBE2J2 Isoform 1, Recombinant, Human, His-Tag (Ubiquitin-conjugating Enzyme E2/ J2, NCUBE2, PRO2121, Ubc6, Ubc6p)

Catalog No : USB-145849
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Product name UBE2J2 Isoform 1, Recombinant, Human, His-Tag (Ubiquitin-conjugating Enzyme E2/ J2, NCUBE2, PRO2121, Ubc6, Ubc6p)
Catalog No USB-145849
Supplier’s Catalog No 145849
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 26.3
Storage -70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 50mM HEPES, pH 7.5, 200mM sodium chloride, 2mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Ubiquitin-conjugating Enzyme E2, J2 (UBE2J2) is a 259 amino acid (aa) member of the Ubiquitin-conjugating (E2) enzyme family with a predicted molecular weight of ~29kD. The human protein shares 100% aa sequence identity with the mouse and rat orthologs. UBE2J2 has an E2 catalytic core domain with an active site cysteine residue that is required for the formation of a thioester bond with Ubiquitin. This enzyme has been reported to be involved in the ER-associated degradation pathway. UBE2J2 has also been shown to interact with the mK3 Ubiquitin ligase (E3) and promote the ubiquitination of hydroxylated residues on major histocompatibility complex class I heavy chains. Source: Recombinant protein corresponding to human UBE2J2 Isoform 1, fused to 6-his tag at N-terminal. Molecular Weight: ~26.3kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.