Imugex

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Categories: Peptides & Proteins / Proteins

Product name			UBE2D2, Recombinant, Human, His-Tag (UbcH5b, Ubiquitin-Conjugating Enzyme E2D 2 (homologous to yeast UBC4/5), UBC4, Ubiquitin Carrier Protein D2, Ubiquitin-Conjugating Enzyme E2-17kD 2, Ubiquitin-Protein Ligase D2, UBCH5B, EC 6.3.2.19, E2(17)KB2, PUBC1, UBC4/5, UBC5B, UBCH4)
Catalog No			USB-220373
Supplier’s Catalog No			220373
Supplier			US Biologicals
Source antigen			Recombinant
Reactivity
Cross reactivity
Applications
Molecular weight			17.73

Storage			-70°C
Other names
Grade			Highly Purified
Purity			~95% (RP-HPLC)
Form			Supplied as a liquid in 50mM Tris, pH 7.5, 150mM NaCl, 10mM DTT, 10% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (RP-HPLC)
Description			UBE2D2 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, 88% and 89% sequence identity with UbcH5b, respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways, including the ubiquitylation of p53 (involving the E3 ligase Hdm2) and IkBa (involving the E3 ligase SCF). Source: Recombinant protein corresponding to human UBE2D2, fused to His-tag. Molecular Weight: ~17.72kD with His Tag Biological Activity: Protein concentration of 100nM-1uM is recommended for in vitro conjugation. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.