WD repeat domain 5, aa1-334, Recombinant, Human (WDR5, BIG3, BIG-3, BMP2-induced 3-kb gene protein, SWD3, WD repeat-containing protein 5)

Catalog No : USB-W1006-13
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Product name WD repeat domain 5, aa1-334, Recombinant, Human (WDR5, BIG3, BIG-3, BMP2-induced 3-kb gene protein, SWD3, WD repeat-containing protein 5)
Catalog No USB-W1006-13
Supplier’s Catalog No W1006-13
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 38.8
Storage -20°C
Other names
Grade Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol, 2mM DTT, 0.1M sodium chloride.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description WDR5, also designated BMP-2-induced gene 3 kb or BIG-3, belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. This protein is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. WDR5 may play a role in its function of accelerating osteoblast differentiation. Source: Recombinant corresponding to aa1-334 of human WDR5 6x his tagged, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MATEEKKPET EAARAQPTPS SSATQSKPTP VKPNYALKFT LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI SDVAWSSDSN LLVSASDDKT LKIWDVSSGK CLKTLKGHSN YVFCCNFNPQ SNLIVSGSFD ESVRIWDVKT GKCLKTLPAH SDPVSAVHFN RDGSLIVSSS YDGLCRIWDT ASGQCLKTLI DDDNPPVSFV KFSPNGKYIL AATLDNTLKL WDYSKGKCLK TYTGHKNEKY CIFANFSVTG GKWIVSGSED NLVYIWNLQT KEIVQKLQGH TDVVISTACH PTENIIASAA LENDKTIKLW KSDC Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.