CIAO1, Recombinant, Human, aa1-339, His-Tag (Probable Cytosolic Iron-sulfur Protein Assembly Protein CIAO1, CIA1, WDR39)

Catalog No : USB-137025
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Product name CIAO1, Recombinant, Human, aa1-339, His-Tag (Probable Cytosolic Iron-sulfur Protein Assembly Protein CIAO1, CIA1, WDR39)
Catalog No USB-137025
Supplier’s Catalog No 137025
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 40
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 20% glycerol, 1mM DTT.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description CIAO1 is essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. This protein is required for the maturation of extra mitochondrial Fe/S proteins and seems to specifically modulate the trans-activation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Source: Recombinant protein corresponding to human CIAO1, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~40kD (362aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKDSLVL LGRVPAHPDS RCWFLAWNPA GTLLASCGGD RRIRIWGTEG DSWICKSVLS EGHQRTVRKV AWSPCGNYLA SASFDATTCI WKKNQDDFEC VTTLEGHENE VKSVAWAPSG NLLATCSRDK SVWVWEVDEE DEYECVSVLN SHTQDVKHVV WHPSQELLAS ASYDDTVKLY REEEDDWVCC ATLEGHESTV WSLAFDPSGQ RLASCSDDRT VRIWRQYLPG NEQGVACSGS DPSWKCICTL SGFHSRTIYD IAWCQLTGAL ATACGDDAIR VFQEDPNSDP QQPTFSLTAH LHQAHSQDVN CVAWNPKEPG LLASCSDDGE VAFWKYQRPE GL Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.