WISP3, Recombinant, Human (WNT1-Inducible-Signaling Pathway Protein 3)

Catalog No : USB-500546
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Product name WISP3, Recombinant, Human (WNT1-Inducible-Signaling Pathway Protein 3)
Catalog No USB-500546
Supplier’s Catalog No 500546
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 37.1
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a lyophilized powder.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description WNT1-inducible-signaling pathway protein 3 (WISP3) is a member of the CCN family of cysteine-rich, glycosylated signalling proteins that mediate several developmental processes, and a member of the WNT1 inducible signalling pathway (WISP) subfamily. Members of this family are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain (IGFBP), von Willebrand factor type C (VWFC) domain, thrombospondin type-1 repeat (TSP type-1) domain, and C-terminal cystine knot-like (CTCK) domain. WISP3 is expressed in mature and fetal kidneys, testis, and in lower levels in the ovary, placenta, prostate, and small intestine. It is necessary for the growth of postnatal skeleton and cartilage homeostasis. Source: Recombinant protein corresponding to human WISP3 expressed in E. coli. Molecular Weight: ~37.1kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of MCF7 cells, and was found to be <0.5ng/mL. Endotoxin: <1EU/ug (LAL) Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.