WISP3, Recombinant, Human (WNT1-Inducible-Signaling Pathway Protein 3)
Catalog No : USB-500546
393.11€
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| Product name | WISP3, Recombinant, Human (WNT1-Inducible-Signaling Pathway Protein 3) | ||
|---|---|---|---|
| Catalog No | USB-500546 | ||
| Supplier’s Catalog No | 500546 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 37.1 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | WNT1-inducible-signaling pathway protein 3 (WISP3) is a member of the CCN family of cysteine-rich, glycosylated signalling proteins that mediate several developmental processes, and a member of the WNT1 inducible signalling pathway (WISP) subfamily. Members of this family are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain (IGFBP), von Willebrand factor type C (VWFC) domain, thrombospondin type-1 repeat (TSP type-1) domain, and C-terminal cystine knot-like (CTCK) domain. WISP3 is expressed in mature and fetal kidneys, testis, and in lower levels in the ovary, placenta, prostate, and small intestine. It is necessary for the growth of postnatal skeleton and cartilage homeostasis. Source: Recombinant protein corresponding to human WISP3 expressed in E. coli. Molecular Weight: ~37.1kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of MCF7 cells, and was found to be <0.5ng/mL. Endotoxin: <1EU/ug (LAL) Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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