Recombinant Rat IL6

Catalog No : IGX-RP392
6019.02€
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Product name Recombinant Rat IL6
Catalog No IGX-RP392
Supplier’s Catalog No IGX-RP392
Supplier ImuGeX
Source antigen E. coli
Reactivity Rat
Cross reactivity
Applications
Molecular weight 22
Storage -70°C
Other names IL-6, IL6<br/>Recombinant Rat Interleukin-6 (IL6)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant rat Interleukin-6 was lyophilized from a 0.2 μm filtered PBS solution.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description IL-6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T cells and B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL-6 after stimulation. IL-6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL-11, and CT-1. All known members of the IL-6 cytokine family induce hepatic expression of acute phase proteins. The IL-6 receptor is expressed on T cells, mitogen-activated B cells, peripheral monocytes and some macrophage and B cell derived tumor cell types. It is not expressed in resting B cells but in resting T cells. The IL-6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.