Recombinant Human IL11
Catalog No : IGX-RP394
2860.92€
0.00€
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| Product name | Recombinant Human IL11 | ||
|---|---|---|---|
| Catalog No | IGX-RP394 | ||
| Supplier’s Catalog No | IGX-RP394 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 19 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IL-11, Adipogenesis inhibitory factor, AGIF, INN=Oprelvekin<br/>Recombinant Human Interleukin-11 (IL11) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in tris buffer and NaCl. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | IL11 is secreted by bone marrow stromal cells (fibroblasts) and is produced also by a number of mesenchymal cells. The IL11 receptor (alpha chain) utilizes gp130 as its signal transducer, which is also a component of other cytokine receptors. The alpha chain of the IL11 receptor has been identified independently as Etl2. IL-1 promotes primary and secondary immune responses in vitro and in vivo and modulates antigen-specific antibody reactions. IL11 promotes the proliferation of IL6 dependent plasmacytoma cell lines in the presence of neutralizing IL6 antibodies. IL11 also stimulates the T cell dependent development of IgG-secreting B cells in spleen cell cultures. IL11 inhibits the differentiation of pre-adipocytes. It induces the synthesis of some acute phase proteins by hepatocytes. | ||
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