Recombinant Human GDNF

Catalog No : IGX-RP409
1960.51€
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Product name Recombinant Human GDNF
Catalog No IGX-RP409
Supplier’s Catalog No IGX-RP409
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 15
Storage -70°C
Other names GDNF, Glial cell line-derived neurotrophic factor, hGDNF, Astrocyte-derived trophic factor, ATF<br/>Recombinant Human Glial-Derived Neurotrophic Factor (GDNF)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant Glial-Derived Neurotrophic Factor was lyophilized from a 0.2 μm filtered solution in 2.5% glycine, 0.5% sucrose, 0.01% Tween80, 5 mM Glutamic acid, pH 4.5.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description GDNF is a disulfide-bonded homodimeric glycosylated protein of 134 amino acids. The amino acid sequences inferred from rat and human cDNAs are 93% identical. The proteins contain seven conserved cysteine residues in the same relative spacing found in all members of the TGF-beta superfamily of proteins. In embryonic midbrain cultures GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.