Recombinant Human FLT3 Ligand (FLT3LG)

Catalog No : IGX-RP421
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Product name Recombinant Human FLT3 Ligand (FLT3LG)
Catalog No IGX-RP421
Supplier’s Catalog No IGX-RP421
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 17
Storage -70°C
Other names Fms-related tyrosine kinase 3 ligand, Flt3 ligand, FLT3LG, Flt3L, SL cytokine
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant FLT-3 Ligand was lyophilized from a 0.2 μm filtered PBS solution pH 7.0.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description FLT-3 ligand promotes long- term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. The human flt-3 ligand also stimulates the proliferation of cells expressing murine flt-3 receptors. In combination with SCF and IL3, flt-3 ligand can cause expansion of cells with the marker spectrum CD34(+) CD38(-). Alone, flt- 3 ligand supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU- GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. flt-3 ligand only has marginal effects on progenitors for erythroid cells and megakaryocytes.