Recombinant Human BMP-3 beta (GDF10)
Catalog No : IGX-RP426
4512.77€
0.00€
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| Product name | Recombinant Human BMP-3 beta (GDF10) | ||
|---|---|---|---|
| Catalog No | IGX-RP426 | ||
| Supplier’s Catalog No | IGX-RP426 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 13 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | BMP-3B, BMP3, BIP, Growth/differentiation factor 10, GDF-10<br/>Recombinant Human Bone Morphogenetic Protein 3B (GDF10) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Recombinant BMP-3b was lyophilized from a 0.2 μm filtered 1.0 mg/mL 10 mM sodium citrate (pH 3.5) containing 10% glycerol._x000D_ _x000D_ | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | BMPs are proteins that act to induce the differentiation of mesenchymal-type cells into chondrocytes and osteoblasts before initiating bone formation. They promote the differentiation of cartilage-forming cells and bone-forming cells near sites of fractures but also at ectopic locations. Some of the proteins induce the synthesis of alkaline phosphatase and collagen in osteoblasts. Some BMPs act directly on osteoblasts and promote their maturation while at the same time suppressing myogenous differentiation. Other BMPs promote the conversion of typical fibroblasts into chondrocytes and are capable also of inducing the expression of an osteoblast phenotype in non-osteogenic cell types. Intracellular signaling following engagement of receptors for some BMP proteins has been shown to involve the action of SMAD proteins. BMP3 is a glycoprotein that is identical with osteogenin. Human and rat mature proteins are 98% identical._x000D_ | ||
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