Recombinant Human IL17A
Catalog No : IGX-RP455
621.63€
0.00€
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| Product name | Recombinant Human IL17A | ||
|---|---|---|---|
| Catalog No | IGX-RP455 | ||
| Supplier’s Catalog No | IGX-RP455 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 16 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IL-17, CTLA-8, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8<br/>Recombinant Human Interleukin-17A (IL17A) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.5) | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | The founding member of the IL17 family of cytokines, IL17A plays an important role in antimicrobial and chronic inflammation. All the six IL17 cytokines (IL17A-F) share a cystine knot fold and are secreted as homodimers. Mature human IL17A shares 60% amino acid sequence identity with rat and mouse IL17A. IL17 cytokines bind to two receptors; IL17RA and IL17RC that together form a heterodimer. The receptor heterodimer is preferred by IL17 ligands, and thus, either IL17RA or IL17RC knockouts completely abolish IL17 signalling. Recombinant human IL17A is a non-glycosylated, 32 kDa disulfide-linked homodimer. | ||
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