Recombinant Mouse GRO gamma (CXCL3)
Catalog No : IGX-RP464
1701.11€
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| Product name | Recombinant Mouse GRO gamma (CXCL3) | ||
|---|---|---|---|
| Catalog No | IGX-RP464 | ||
| Supplier’s Catalog No | IGX-RP464 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Mouse | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 8 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | C-X-C motif chemokine 3, Dendritic cell inflammatory protein 1, Dcip1, Gm1960 <br/>Recombinant Mouse Growth-Regulated Oncogene Gamma (CXCL3) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in Phosphate and NaCl | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Growth regulated oncogene- gamma belongs to the family of chemotyctic cytokines called chemokines. It is identical with MGSA (melanoma growth stimulatory activity) and the new designation is CXCL3. This factor is known mainly because of its chemotactic activity. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B. | ||
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