Recombinant Human Resistin (RETN)

Catalog No : IGX-RP478
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Product name Recombinant Human Resistin (RETN)
Catalog No IGX-RP478
Supplier’s Catalog No IGX-RP478
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 10
Storage -70°C
Other names FIZZ3, Adipose tissue-specific secretory factor, ADSF, HXCP1, RSTIN, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant human Resistin was lyophilized from a 0.2 μm filtered PBS solution.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90% in 3T3-L1 adipocytes.