Recombinant Human B-cell Activating Factor (TNFSF13B)

Catalog No : IGX-RP486
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Product name Recombinant Human B-cell Activating Factor (TNFSF13B)
Catalog No IGX-RP486
Supplier’s Catalog No IGX-RP486
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 18
Storage -70°C
Other names B cell Activating Factor belonging to the TNF family, BAFF, Tumor necrosis factor ligand superfamily member 13B, TNFSF13B, TNFSF20, B lymphocyte stimulator, BLys, THANK, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1, CD_antigen=CD257
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant Human BAFF was lyophilized from a 0.2 μm filtered solution in PBS, pH 7.5.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.