Recombinant Mouse Stem Cell Factor (KITLG)

Catalog No : IGX-RP490
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Product name Recombinant Mouse Stem Cell Factor (KITLG)
Catalog No IGX-RP490
Supplier’s Catalog No IGX-RP490
Supplier ImuGeX
Source antigen E. coli
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 18.9
Storage -70°C
Other names SCF, Kit ligand, c-Kit ligand, Hematopoietic growth factor KL, Mast cell growth factor, MGF, Steel factor
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in 20mM Tris and 5% trehalose (pH 7.5)
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description SCF is a stromal cell-derived cytokine synthesized by fibroblasts and other cell types. SCF promotes proliferation and early differentiation of cells at the level of multipotential stem cells. It has been suggested that SCF is essential for optimal production of various hematopoietic lineages. The receptor for SCF, designated SCFR(CD117), is the oncogene designated as KIT. The biological activities of SCF are synergised considerably by colony stimulating factors GM-CSF and G-CSF, and also by IL-7, Epo and some other growth and differentiation factors. In combination with IL-7, SCF stimulates the proliferation of pre-B cells. SCF is also a potent chemoattractant for cells, for example, mast cells, expressing the kit receptor.