Recombinant Human TRAIL (TNFSF10)

Catalog No : IGX-RP495
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Product name Recombinant Human TRAIL (TNFSF10)
Catalog No IGX-RP495
Supplier’s Catalog No IGX-RP495
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 19.5
Storage -70°C
Other names TRAIL, Tumor necrosis factor (Ligand) family member 10, TNFSF10, Apo2 Ligand, TL2<br/>Recombinant Human TNF-Related Apoptosis-Inducing Ligand (TNFSF10)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description A cytotoxic protein, TRAIL initiates apoptosis in tumor cells by binding the death-signalling receptors; DR4 and DR5. In its active conformation, TRAIL forms homotrimers. TRAIL transcripts have been shown to be constitutively expressed in a variety of human tissues. There are five known TRAIL receptors: two which transduce apoptotic signals, two which function as decoys to block TRAIL-induced apoptosis and osteoptotegrin.