Recombinant Human Fractalkine (CX3CL1)

Catalog No : IGX-RP505
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Product name Recombinant Human Fractalkine (CX3CL1)
Catalog No IGX-RP505
Supplier’s Catalog No IGX-RP505
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 8.9
Storage -70°C
Other names C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Fractalkine is a type I membrane protein that signals through the CX3CR1 receptor. The extracellular domain of Fractalkine is released by protease cleavage – producing soluble Fractalkine. Fractalkine has been found in many tissues and shown to be up-regulated in endothelial cells and microglia in response to inflammatory signals. Fractalkine is also involved in leukocyte adhesion as well as attracting monocytes, microglia cells and NK cells.