Recombinant Human TNFRSF10B
Catalog No : IGX-RP532
910.32€
0.00€
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| Product name | Recombinant Human TNFRSF10B | ||
|---|---|---|---|
| Catalog No | IGX-RP532 | ||
| Supplier’s Catalog No | IGX-RP532 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TRAIL receptor 2, TRAIL-R2, CD262, TNF-related apoptosis-inducing ligand receptor 2 | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a solution in PBS (pH 7.4) with 5% Mannitol, 5% Trehalose and 0.02% Tween 80. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | TNFRSF10B is a member of the TNFR superfamily and is a cell surface receptor that is involved in apoptosis. It contains an intracellular death domain and can be activated by binding to either membrane-anchored or soluble TRAIL/Apo2L. Diseases associated with TNFRSF10B include squamous cell carcinoma, head and neck and oral cavity cancer. Among its related pathways are Akt Signaling and Akt Signaling. It is closely related to TRAIL R1/DR4, sharing 55% amino acid sequence identity. | ||
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