Recombinant Human 4-BBL (TNFSF9)

Catalog No : IGX-RP533
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Product name Recombinant Human 4-BBL (TNFSF9)
Catalog No IGX-RP533
Supplier’s Catalog No IGX-RP533
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 19.6
Storage -70°C
Other names TNFSF9, CD137L, 4BBL
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form coming soon
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein.