Recombinant Human 4-BBL (TNFSF9)
Catalog No : IGX-RP533
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Product name | Recombinant Human 4-BBL (TNFSF9) | ||
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Catalog No | IGX-RP533 | ||
Supplier’s Catalog No | IGX-RP533 | ||
Supplier | ImuGeX | ||
Source antigen | E. coli | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 19.6 |
Storage | -70°C | ||
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Other names | TNFSF9, CD137L, 4BBL | ||
Grade | Highly Purified | ||
Purity | >95% as determined by SDS-PAGE | ||
Form | coming soon | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | >95% as determined by SDS-PAGE | ||
Description | Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein. |
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