Recombinant Human Artemin (ARTN)
Catalog No : IGX-RP540
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Product name | Recombinant Human Artemin (ARTN) | ||
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Catalog No | IGX-RP540 | ||
Supplier’s Catalog No | IGX-RP540 | ||
Supplier | ImuGeX | ||
Source antigen | E. coli | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 12.2 |
Storage | -70°C | ||
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Other names | Enovin, Neublastin | ||
Grade | Highly Purified | ||
Purity | >95% as determined by SDS-PAGE | ||
Form | Lyophilized from a 0.2 µm filtered solution in HCl (with BSA as a carrier protein) | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | >95% as determined by SDS-PAGE | ||
Description | Artemin is a disulfide-linked member of the glial cell line-derived homodimeric neurotrophic factor (GDNF) family which all signal via a multicomponent receptor system composing of a high-affinity binding component (GFRα1-4) and a common signalling receptor tyrosine kinase (RET). Artemin prefers the receptor GFRα3-RET, but will use the others as an alternative. Artemin promotes the survival and growth of peripheral and central neurons, including dopaminergic neurons in the mid-brain; and plays an important role in the development of sensory and sympathetic neurons. |
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