Recombinant Human IL17F
Catalog No : IGX-RP553
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Product name | Recombinant Human IL17F | ||
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Catalog No | IGX-RP553 | ||
Supplier’s Catalog No | IGX-RP553 | ||
Supplier | ImuGeX | ||
Source antigen | E. coli | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 15.2 |
Storage | -70°C | ||
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Other names | Cytokine ML-1 | ||
Grade | Highly Purified | ||
Purity | >95% as determined by SDS-PAGE | ||
Form | Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein) | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | >95% as determined by SDS-PAGE | ||
Description | Interleukin 17F is a disulfide-linked homodimeric protein belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL-17 family is inducible by IL15 and IL23, and IL17F induces T-cell and PBMC activation and proliferation. It also performs cartilage matrix turnover and angiogenesis prevention. Out of the IL-17 family, IL17F is the most homologous to IL17 and dimerizes in a way similar to that of nerve growth factors (NGF) and other neurotrophins. |
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