Recombinant Rat IL2
Catalog No : IGX-RP578
161.38€
0.00€
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Product name | Recombinant Rat IL2 | ||
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Catalog No | IGX-RP578 | ||
Supplier’s Catalog No | IGX-RP578 | ||
Supplier | ImuGeX | ||
Source antigen | E. coli | ||
Reactivity | Rat | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 15.6 |
Storage | -70°C | ||
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Other names | T-cell growth factor | ||
Grade | Highly Purified | ||
Purity | >95% as determined by SDS-PAGE | ||
Form | Lyophilized from a 0.2 µm filtered solution in ammonium acetate and glycerol (with BSA as a carrier protein) | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | >95% as determined by SDS-PAGE | ||
Description | Rat IL2, also known as T-cell growth factor, is a secreted immunoregulatory cytokine produced by T-cells due to antigenic or mitogenic stimulation. IL2 binds to the IL2 receptor, which is found in T and B cells and natural killer cells, and is composed of three distinct components: the cytokine specific α-chain, and the β– and γc-subunits. Its receptor complex IL2 induces the proliferation of T cells, generation of cytotoxic T lymphocytes (CTLs), proliferation and synthesis of immunoglobulin by B cells, and the survival of natural killer cells. Its heterotrimeric receptor complex is also shared by Interleukin 4 (IL4) and Interleukin 7 (IL7) by its gamma chain, and receptor signalling is essential for its expression and differentiation of regulatory T cells in the immune response. |
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